Blake A. Isernhagen, MD

Blake A. Isernhagen, MD

Blake A. Isernhagen, MD returned home in 2016 to Kentucky, where he grew up and went to high school. He received his undergraduate and medical degrees with Distinction from The University of Oklahoma, where he was recognized for academic excellence in the Alpha Omega Alpha Honorary Medical Society. Dr. Isernhagen did his Ophthalmology Residency at The Dean A. McGee Eye Institute at the University of Oklahoma and then moved on to an advanced Uveitis and Retinal training at the Bascom Palmer Eye Institute in Miami. He completed his fellowship in Vitreoretinal Surgery at the University of British Columbia, where he served as the distinguished William H. Ross Fellow. He has been active in lecturing, teaching, as well as researching uveitis and retinal disease. Dr. Isernhagen also has a passion for helping others and has served in overseas missions providing eye care and training in underserved areas, including China and Africa.

What are your interests?

Prior to training in vitreoretinal surgery, I specialized in uveitis and medical retina. I have a special interest in the diagnosis and management of uveitis, in particular, posterior and panuveitis. These ocular diseases require special attention to the patient’s medical history and can be challenging to both diagnosis and appropriately treat. I find great joy investing in these patients and stabilizing their ocular disease.

Each patient with a retinal detachment is a unique individual, and I enjoy the challenge of planning the optimal strategy for a successful surgical outcome. This involves either alone or in combination pneumatic retinopexy, scleral buckling, or vitrectomy.

What research are you working on?

During my fellowships I was involved in national clinical trials involving age related macular degeneration, diabetic retinopathy, macular telangiectasia, and uveitis.  I presented papers at the Association for Research in Vision and Ophthalmology on Autoimmune Retinopathy and Birdshot Chorioretinopathy.  I look forward to being involved in many clinical studies that are supported by Retina Associates of Kentucky.

What led you to choose Retina Associates?

I grew up in Lexington, KY and was fortunate to observe my father as an active vitreoretinal surgeon with Retina Associates of Kentucky.  I was impressed how retinal treatments had a profound impact on patient’s vision and life.  Additional experiences in medical school and residency lead me to pursue specialties in uveitis and vitreoretinal surgery.  I was honored to be chosen to join the nationally recognized group of physicians with great reputations at Retina Associates of Kentucky.  I completed a fellowship in uveitis in hope I could bring additional expertise to the group.

What do you enjoy outside of Medicine?

Outside of medicine I enjoy spending time with my wife Kallista, our sons Brody (2014) and Boston (2016), and my parents and sister who also live in Lexington.  We enjoy traveling including road-trips to see our extended family in Oklahoma and Northwest Kansas. Some of my hobbies are golf, snow skiing, fishing, music, fitness training, road biking, and remote control model airplanes.   

Links and Information

Dr. Blake educates on how new technology targets treatment for Uveitis


1700 Winchester Avenue
Ashland, Kentucky 41101
Toll Free: (800) 627-2020
Phone: (859) 263-3900
Main Fax: (859) 263-3757
Scheduling Fax: (859) 264-2911


120 North Eagle Creek Drive
Suite 500
Lexington, Kentucky 40509
Toll Free: (800) 627-2020
Office: (859) 263-3900
Main Fax: (859) 263-3757
Scheduling Fax: (859) 264-2911


6450 Dutchman's Parkway
Louisville, Kentucky 40205
Toll Free: (800) 627-2020
Office: (502) 895-2600
Main Fax: (502) 895-4002
Scheduling Fax: (859) 264-2911

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